Masters of Health Magazine November 2018 | Page 40

Conclusions:

1. The expression of apoptosis markers in patients with CIN II is significantly increased (BAX - 185.3 ± 17.4 H-score, bcl-2 - 143.9 ±

2.6 H-score) compared to expression with CIN I (BAX - 166.6 ± 18.4 H-score, bcl-2 - 138.2 ± 3.6 H-score).

2. The expression of immature dendritic cells CD1a (+) increases significantly with CIN II to 220.2 ± 18.4 H-score, CINI is 92.9 ± 6.7 H-score (p <0.05).

3. The expression of mature dendritic cells CD56 (+) increases significantly with a CIN I of 204.3 ± 9.8 H-score, with a CIN II of 60.9 ± 3.4 H-score, which allows us to consider these figures as prediction markers .

4. The presence of a correlation relationship of average strength between the indices of bcl-2 and CD1a (r = 0.54), indicating that the pathogenetic processes of cell proliferation are related.

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