Tumors actively sequester estrogen. Normally excess estrogen is processed by the liver. But estrogen overload or liver damage may drive tumor formation. Then cancer cells dramatically upregulate estrogen receptors (ERα and ERβ) on their cell membrane to pull estrogen out of the bloodstream and transport it into the cell for local processing.
In each case — fructose, ethanol, and estrogen — the body is not malfunctioning. It is intelligently delegating critical liver functions to tumor tissue when its primary organ can no longer keep up. This “second liver” phenomenon is one of the clearest examples of the body’s adaptive genius within the Toxin Sequestration Theory.
“Fuel sources” for cancer growth
In Thomas Seyfried’s metabolic theory of cancer, he argues that cancer just wants to grow uncontrollably, so it pulls in glucose and glutamine as fuel sources for its growth. Viewing glucose and glutamine solely as fuel sources is fairly mainstream at this point. But is it correct?
What if there was a deeper point to cancer’s love for glucose and glutamine?
(1) Glucose
For glucose, the key to understanding its role in cancer is to view it like every other chemical we’ve discussed above. In my view, it’s no different from PFAS, microplastics, mycotoxins, or ethanol. GLUCOSE IS A TOXIN. The fact that glucose plays some physiological role is irrelevant in the today’s modern diet full of candy and sodas.
The easiest way to see that glucose is a toxin is to observe the massive amount of tissue damage that diabetics have - a phenomenon called “diabetes complications”.