OPs can reach children by various routes of exposure via fetal exposure crossing the placenta and in breast milk. The blood brain barrier is not developed until after age one and does not protect the infant from unwanted chemicals crossing into the brain.48
There is significant genetic variability of the PON1 gene which will impact susceptibility to OPs. PON1 can be seen as a biomarker of susceptibility to neurodevelopment effects.49
Due to its toxicity, OPs are being phased out in many parts of the world. However, the usage forecast in Africa has been estimated to continue to grow at the rate of 4.8% between 2017-2022, with South Africa and Egypt requiring the highest demands.50
Pesticides and the link to neurodevelopment disorders
ASD is now a global epidemic facing children and as presented in the graph below:
Prevalence of autism spectrum disorder among children in select countries worldwide as of 2020 (per 10,000 children)51
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How could we have ever believed that it was a good idea to grow our food with poisons?
-Jane Goodall