However, because they are adult, their ability to generate a full spectrum of growth factors is limited, as is their ability to provide the appropriate exosomes, sececretomes, and microRNa. Extracellular matrix is not captured either. Only one section of the orchestra is captured in this process and it limits the ability to amplify or upregulate the recipient’s regenerative response.
Placental Tissue Allografts
This regenerative therapy brings all of the sections of the orchestra into play. This donor material is obtained from young healthy pregnant women who are scheduled for elective C-section, then screened to insure that they have not engaged in any unhealthy behaviors, that their medical history is clean, and they are disease free. This is determined with questionnaires and by testing of their blood. At the time of C-Section, the amniotic fluid is captured as the baby is being delivered by the obstetrician. Then, after a healthy baby is delivered, the placental tissue is collected. The fluid and placental membranes are tested to insure that they are free of any bioburden such as viruses, bacteria, fungus, or parasites. The tissue that is obtained is then processed in sterile clean rooms and made into human tissue allografts that can be used on any other person, since there are no HLA antigens that if present could cause a reaction. Amniotic membrane and amniotic fluid are available to physicians “off-the-shelf”, no surgical procedures are needed to administer the therapy.
How do we know the power of Placental tissue as a potent promoter of regenerative powers?
To be Continued in January 2018 issue.