Masters of Health Magazine August 2025 | Page 48

Diminished Zeta Potential and Acidosis:

Altered zeta potential can drive inflammation and what is commonly termed “infection”, but in reality is a die-off and/or overgrowth of certain microorganisms as the body is trying to re-establish the colloidal stability or homeostasis. The inflammatory processes subsequently also alter zeta potential by changing the local chemical environment, which in turn can affect the behavior of immune cells and proteins. Acidosis is a condition characterized by an excessive accumulation of acid leading to a decrease in blood pH below the normal and tightly regulated range of 7.35–7.45. Even small deviations from this range can be dangerous or even life threatening. Note that the pH of the blood and urine are different parameters - blood pH is tightly controlled, while urine pH (which you can measure with pH strips) is highly variable, as urine is filtrated from the blood, carrying away waste products which are typically acidic.

Common Causes of Increased Body Acidity:

  • Diabetic ketoacidosis:

    When insulin is low, the body burns fat, producing ketone bodies (acids like acetoacetate and beta-hydroxybutyrate).

  • Lactic acidosis:

    From intense exercise or oxygen deficiency; leads to a buildup of lactic acid (this was my problem which I addressed with ZetaAid).

  • Renal failure:

    The kidneys fail to excrete enough hydrogen ions or reabsorb bicarbonate, increasing acid buildup.

  • Hypoventilation:

    Poor breathing leads to CO₂ retention, forming carbonic acid in the blood (respiratory acidosis).

  • Seen in COPD, sleep apnea, or drug overdose.

  • Note that this is also seen with prolonged mask wearing. Even 30 minutes of wearing a mask can start inducing acidosis in some people, and that’s exactly why the covid planners forced mask mandates with such zeal. This is because flu and common colds are triggered by acidosis which results in the body trying to reestablish normal homeostasis, not by any traveling viruses! Fraudulent PCR tests react to pH acidity levels, and that’s why they can be triggered positive simply by drinking Coca-Cola or fruit juice.

  • High protein intake and low fruit and vegetable intake:

    Reduces base (alkaline) buffering from minerals like potassium and magnesium. Induces keto-acidosis. This is why I am not a proponent of carnivore diets or high protein diets. They may be fine short-term for losing weight but long-term diets like this may damage kidneys.

  • Dehydration:

    Concentrates acids and reduces kidney acid excretion.

  • Alcohol:

    Especially in excess, can produce acidic metabolites and impair liver function.

  • Starvation or prolonged fasting:

    Leads to ketone production, like in ketoacidosis.

  • Almost all prescription drugs and supplements  increase acidity levels and are excreted via the kidneys, putting additional load on them.

  • Trace metals - extreme cationic offenders include aluminum, copper, iron, lead, manganese, silicon, tin, zinc.

  • The body keeps blood pH stable in a tight range to maintain enzyme activity, oxygen delivery, and cell function. It uses the urine as a dumping system to get rid of hydrogen ions (H⁺) or bicarbonate (HCO₃⁻), helping to maintain blood pH balance. The blood pH is very tightly controlled, while urine pH will vary widely during the day depending on diet and lifestyle habits and other factors. The range of 4.5 to 8.0 is considered normal for urine pH. However, constantly staying in the highly acidic urine pH levels may indicate that the system is strained and hydration and zeta potential may be affected.

    Terrain and Microbiome, Desiccation, Loss of Zeta Potential and Aging.

    This topic is very much lacking proper studies, so this is purely speculative reasoning. Let’s think about the body as terrain. What is terrain? It literally means “dirt” - soil, land, Earth, i.e. material and nutrient substrate for the living things to reside on. In human (or animal) body the body itself is the place where microbiome resides. Both the skin and the gastrointestinal tract (GI) constitute the surface areas of the body, which is wrapped around the GI tract to consume the water and nutrients and expel byproducts/waste.

    Soil pH plays a critical role in crop growth by directly affecting nutrient availability, microbial activity, and overall soil health. Most crops grow best in a slightly acidic to neutral pH range (around 6.0 to 7.0), where essential nutrients like nitrogen, phosphorus, and potassium are most accessible to plant roots. When the soil is too acidic or too alkaline, certain nutrients become less available or even toxic. Additionally, soil pH influences the activity of beneficial microorganisms that help decompose organic matter and fix nitrogen, further impacting plant health.

    In nature, aging and death manifest as gradual desiccation: plants yellow, shrink and die off, humans and animals visibly shrink and wrinkle with age. In this process of aging and death, the loss of water is not the only factor. In fact, having researched this topic so far, I can say that it is likely the loss of zeta potential of the aqueous colloid of the body that results in the loss of the total volume of water carried in the colloid - this loss results in the visible shrinking of the overall structure/body

    In both plants and humans, in the energy producing structures, such as in mitochondria the pH gradient is alkaline (7.7- 8.0) and its tight regulation is crucial for the system. Disturbances in pH (too acidic or too alkaline) accompanied by under- or -over supply of water may inhibit some species and promote others. Thriving ecosystems fed by freshwater streams have on average slightly acidic to neutral pH, just like normal soils, however dying swamps (bogs) have very high acidity levels (3.5-5.5), while not in principle lacking fresh water.

    Same general principles should apply to the human body. The microbial flora present throughout human body contains aerobic and anaerobic species and they play crucial role both in health and disease. I am not an expert on gut and other microbes, but as an example, a drop below pH 5.5 in the colon can inhibit beneficial microbes and favor potentially dangerous species (e.g., Clostridium difficile).

    Implications for Vaccine Injuries and Other Chronic Illness:

    In a recent interview I described what happens with cationic lipids (LNPs in mRNA shots) get injected into the blood stream, comparing the effect to “toaster in the bathtub” (video clip courtesy of Sense Receptor  on X, includes transcript). Many researchers published images and video of what happens when live blood is mixed with the mRNA shots containing cationic LNPs. The effect of mixing the injection substance with blood is immediate and dramatic - the red blood cells deteriorate, break and leak hemoglobin, multiple crystallized structures appear (precipitate out of the colloid) and white blood cells disappear.

    Here are some examples from researchers in Australia and NZ: