Sandy sanderson
“My heart restored,
My waters cleansed,
The power surges
In love to mend.”
CEO of Elektra Magnesium
Magnesium is Crucial for Heart Health. Part 3.
Research is not yet conclusive about exactly how this mechanism works, except the observations are that low magnesium in and of itself can trigger release of adrenaline, which facilitates entry of calcium into the channels. Merely a low magnesium status can open the door to calcium entry.
Magnesium has a very large hydration shell. Its six waters of hydration are held more tightly to magnesium than to most other cations. The difference between its dehydrated and most hydrated state involves a volume change of almost 400-fold, over an order of magnitude larger than for any other cation.
It is likely that the cellular loss of hydration resulting from a fall in magnesium levels creates more gaps in the cell membrane, which then allows more calcium into the channels.